progesterone capsules
Progesterone capsules can be prescribed for specific cyclical disorders characterised by a shortage of progesterone in the second half of the cycle. In addition, it is often prescribed as a component of in vitro fertilisation (IVF) treatment. This section is limited to its use in fertility treatments.
A woman’s natural hormone production is usually suppressed during an IVF cycle (by the use of GnRH agonists or antagonists). This also prevents natural progesterone production during the second half of an IVF cycle after egg collection ( the puncture). This must be rectified because progesterone is necessary for preparing the womb lining for the implantation of a fertilised egg (embryo). Consequently, progesterone capsules are prescribed after the puncture. (Alternatively, hCG injections can be given.)
how it works
Progesterone works in exactly the same way as naturally occurring progesterone to prepare the lining of the womb for pregnancy.
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how it is administered
Progestan capsules are licensed for oral use. In order to limit the chances of potential side effects, in practice you are often advised to put them into your vagina. (The progesterone is absorbed across the vaginal wall and into the blood circulation.) A normal dosage is two tablets twice a day, starting on the day of the puncture and for at least fifteen days.
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possible side effects
When these pills are taken vaginally, they cause a vaginal secretion and they can also delay the start of menstruation for a few days. It is particularly important you are aware of this so you don’t immediately view a delay in your period as a sign of pregnancy.
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